African clawed frog Totally Explained

Everything about Xenopus Laevis totally explained

The African clawed frog (Xenopus laevis, also known as platanna) is a species of South African aquatic frog of the genus Xenopus. It is up to 12 cm long with a flattened head and body, but no external ear or tongue. Its name derives from the three short claws on each of its hind feet, which it probably uses to stir up mud to hide it from predators.
The genus is found throughout much of Europe, North America, South America and Africa.

Description

These frogs are plentiful in ponds and rivers within the southeastern portion of Sub-Saharan Africa. They are aquatic and often a yellowish, grey color. Albino varieties are sold as pets. They reproduce by eggs (see frog reproduction).
   These frogs tend to live 5 to 15 years but some have been recorded to live to be nearly 30 years. They shed every season, and eat their own shed skin.
   Although lacking a vocal sac, the males make a mating call of alternating long and short trills, by contracting the intrinsic laryngeal muscles. Most unusually, females also answer vocally, signaling either acceptance (a rapping sound) or rejection (slow ticking) of the male.
   They also swim very fast, and can eat smaller fish, such as minnows and guppies. When they eat, the food isn't actually held down very well, and occasionally, the fish, or bug, can actually escape before being forced back into the mouth by the frog's front hands.

Use in genetic research

Although X. laevis doesn't have the short generation time and genetic simplicity generally desired in genetic model organisms, it's an important model organism in developmental biology. X. laevis takes 1 to 2 years to reach sexual maturity and, like most of its genus, it's tetraploid. However, it does have a large and easily manipulable embryo. The ease of manipulation in amphibian embryos has given them an important place in historical and modern developmental biology. A related species, Xenopus tropicalis, is now being promoted as a more viable model for genetics. Roger Wolcott Sperry used X. laevis for his famous experiments describing the development of the visual system. These experiments led to the formulation of the Chemoaffinity hypothesis. Xenopus oocytes provide an important expression system for molecular biology. By injecting DNA or mRNA into the oocyte or developing embryo, scientists can study the protein products in a controlled system. This allows rapid functional expression of manipulated DNAs (or mRNA). This is particularly useful in electrophysiology, where the ease of recording from the oocyte makes expression of membrane channels attractive. One challenge of oocyte work is eliminating native proteins that might confound results, such as membrane channels native to the oocyte. Translation of proteins can be blocked or splicing of pre-mRNA can be modified by injection of Morpholino antisense oligos into the oocyte (for distribution throughout the embryo) or early embryo (for distribution only into daughter cells of the injected cell). X. laevis is also notable for its use as the first well-documented method of pregnancy testing when it was discovered that the urine from pregnant women induced X. laevis oocyte production. Human chorionic gonadotropin (HCG) is a hormone found in substantial quantities in the urine of pregnant women. Today, commercially available HCG is injected into Xenopus males and females to induce mating behavior and breed these frogs in captivity at any time of the year.

As a pest

When African clawed frogs are imported into non-native countries, they've the capacity to wreck entire ecosystems by eating native wildlife such as fish and turtles that have no natural defense against these creatures.
In 2007, these frogs invaded a pond in San Francisco, where much debate exists on how to terminate these creatures and keep them from spreading. It is unknown if these frogs entered the San Francisco ecosystem through intentional release or escape into the wild.
Because these frogs are immune to the fungi Batrachochytrium dendrobatidis (a chytridomycota) and B. dendrobatidis has been traced back to the habitat of Xenopus laevis in Africa, many scholars believe it's the source of the worldwide frog population crash. Due to its extensive use in obstetrics and research, it appears Xenopus laevis has carried B. dendrobatidis with it out of Africa to all over the world, causing chytridomycosis and eventually death in native frogs naïve to the fungi.

Further Information

Get more info on 'Xenopus Laevis'.

External Link Exchanges

Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:

<a href="http://african_clawed_frog.totallyexplained.com">African clawed frog Totally Explained</a>

Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned.